β-nicotinamide mononucleotide (NMN)

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Selleck Chemicals

S5259-25MG

€144,00 EUR
€144,00 EUR
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β-nicotinamide mononucleotide (NMN) is an inhibitor of Sirtuins used in studies of Epigenetic Regulation. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation in aging, cancer, and epigenetics models.

By inhibiting Sirtuins, β-nicotinamide mononucleotide (NMN) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In aging, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sirtuins
  • Pathway perturbation studies connected to Epigenetic Regulation
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, β-nicotinamide mononucleotide (NMN) is appropriate when a defined chemical perturbant is needed to connect Sirtuins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sirtuins
Target Class:
Epigenetic Regulator
Pathways:
Epigenetic Regulation
Research Area:
Aging • Cancer • Epigenetics • Metabolism
CAS No.:
1094-61-7
Molecular Weight:
334.22
Formula:
C₁₁H₁₅N₂O₈P
SMILES:
C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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