Bedaquiline
Selleck Chemicals
SKU:S5623-10MG
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Bedaquiline is an inhibitor of ATPases used in studies of enzyme regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to catalytic activity, substrate turnover, and enzymatic regulation in cell signaling and infectious disease models.
By inhibiting ATPases, Bedaquiline can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cell signaling and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving ATPases
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
- Phenotypic profiling in cell signaling and infectious disease models
Overall, Bedaquiline is appropriate when a defined chemical perturbant is needed to connect ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- ATPases
- Target Class:
- Enzyme
- Research Area:
- Cell Signaling • Infectious Disease
- CAS No.:
- 843663-66-1
- Molecular Weight:
- 555.50
- Formula:
- C₃₂H₃₁BrN₂O₂
- SMILES:
- CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
- InChIKey:
- QUIJNHUBAXPXFS-XLJNKUFUSA-N
- PubChem:
- 5388906
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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