ASP2453

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Selleck Chemicals

E1071-5MG

€842,00 EUR
€842,00 EUR
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ASP2453 is an inhibitor of KRAS used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.

By inhibiting KRAS, ASP2453 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving KRAS
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer and cell signaling models

Overall, ASP2453 is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
KRAS
Target Class:
Other
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
2241719-73-1
Molecular Weight:
747.85
Formula:
C₄₀H₄₈F₃N₇O₄
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.