Aquaporin-8 (AQP8) Antibody - Western Blot Validated
BiCell Scientific
SKU:20108-WB-50UL
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Protein Function
This antibody supports efforts to examine Aquaporin-8 (AQP8) and interpret it within interaction networks. Aquaporin-8 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol AQP8.
Experimental Applications
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Workflow Perspective
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
If your study spans multiple model systems, it can help to define a shared reference condition for Aquaporin-8 so cross-sample contrasts stay meaningful.
The denaturing-format option supports mechanistic reading of Aquaporin-8 (AQP8) when interactions and context are the focus.
- Targets:
- AQP8
- Research Area:
- Metabolism
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse Aquaporin-8 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O94778
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 83.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C