Anoctamin-1 (ANO1 or TMEM16A) (N-Terminus) Antibody
BiCell Scientific
SKU:20531-50UL
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Protein Function
This antibody enables you to evaluate Anoctamin-1 N-Terminus with a direct, biology-first readout. Anoctamin-1 N-Terminus is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Focus on trends across conditions rather than single-point snapshots.
Monitoring Anoctamin-1 N-Terminus alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
Workflow Perspective
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
If your study spans multiple model systems, it can help to define a shared reference condition for Anoctamin-1 N-Terminus so cross-sample contrasts stay meaningful.
For challenging targets, pairing Anoctamin-1 N-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Select the regular format version to keep Anoctamin-1 N-Terminus interpretation aligned with your workflow goals.
- Targets:
- ANO1
- Research Area:
- Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the N-terminal cytoplasmic region of mouse Anoctamin-1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q5XXA6
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C