Amyloid-beta Precursor Protein (APP or AD1) Antibody

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BiCell Scientific

SKU:51475-50UL

Regular price €305,00 EUR
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Size
Blocking Peptide
Quantity
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Protein Function

Use this antibody to assess Amyloid-beta Precursor Protein (APP) in your model system. Amyloid-beta Precursor Protein is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Look for shifts in distribution that track with phenotype changes.

Tracking Amyloid-beta Precursor Protein can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Experimental Applications

Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.

Common experimental questions that benefit from target tracking include:

  • condition-to-condition comparisons with matched controls
  • localization shifts between cytoplasm, membrane, and nucleus
  • time-resolved changes following stimulation or inhibition
  • interaction patterns within multi-protein complexes

Workflow Perspective

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Amyloid-beta Precursor Protein patterns can be compared across experiments without guesswork.

When interpreting Amyloid-beta Precursor Protein, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Select the regular format version to keep Amyloid-beta Precursor Protein (APP) interpretation aligned with your workflow goals.

Targets:
APP
Research Area:
Aging • Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of human APP protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P05067
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C