Aminophylline
Selleck Chemicals
SKU:S1673-25MG
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Aminophylline is an inhibitor of PDE and Adenosine Receptors used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular, inflammation, and metabolism models.
By inhibiting PDE and Adenosine Receptors, Aminophylline can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cardiovascular, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving PDE and Adenosine Receptors
- Pathway perturbation studies connected to GPCR Signaling
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, Aminophylline is appropriate when a defined chemical perturbant is needed to connect PDE and Adenosine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- PDE • Adenosine Receptors
- Target Class:
- Enzyme
- Pathways:
- GPCR Signaling
- Research Area:
- Cardiovascular • Inflammation • Metabolism • Neuroscience
- CAS No.:
- 317-34-0
- Molecular Weight:
- 420.43
- Formula:
- C₁₆H₂₄N₁₀O₄
- SMILES:
- CN1C2=C(C(=O)N(C1=O)C)NC=N2.CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N
- InChIKey:
- FQPFAHBPWDRTLU-UHFFFAOYSA-N
- PubChem:
- 9433
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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