Amiloride HCl

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Selleck Chemicals

S1811-50MG

€144,00 EUR
€144,00 EUR
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Amiloride HCl is an inhibitor of Sodium Channels and Calcium Channels used in studies of Calcium Signaling. It is especially relevant in cardiovascular, cell signaling, and neuroscience models, where defined compound exposure can be linked to calcium flux, excitability, and secretion-linked signaling.

By inhibiting Sodium Channels and Calcium Channels, Amiloride HCl can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cardiovascular, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sodium Channels and Calcium Channels
  • Pathway perturbation studies connected to Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Amiloride HCl is appropriate when a defined chemical perturbant is needed to connect Sodium Channels and Calcium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sodium Channels • Calcium Channels
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
2016-88-8
Molecular Weight:
266.09
Formula:
C₆H₈ClN₇O·HCl
SMILES:
C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.