AMG-333

1 1

Selleck Chemicals

S6638-5MG

€144,00 EUR
€144,00 EUR
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AMG-333 is an antagonist of TRP Channels used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in cell signaling and neuroscience models.

By blocking TRP Channels, AMG-333 can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cell signaling and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TRP Channels
  • Pathway perturbation studies connected to Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, AMG-333 is appropriate when a defined chemical perturbant is needed to connect TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TRP Channels
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Cell Signaling • Neuroscience
CAS No.:
1416799-28-4
Molecular Weight:
453.32
Formula:
C₂₀H₁₂F₅N₃O₄
SMILES:
C1=CC(=C(N=C1)C(C2=CC(=C(C=C2)OC(F)(F)F)F)NC(=O)C3=NC=C(C=C3)C(=O)O)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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