AGK2

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Selleck Chemicals

SKU:S7577-5MG

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AGK2 is an inhibitor of Sirtuins used in studies of Epigenetic Regulation. It is especially relevant in aging, cancer, and epigenetics models, where defined compound exposure can be linked to chromatin-state control, histone modification, and transcriptional regulation.

By inhibiting Sirtuins, AGK2 can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In aging, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sirtuins
  • Pathway perturbation studies connected to Epigenetic Regulation
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, AGK2 is appropriate when a defined chemical perturbant is needed to connect Sirtuins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sirtuins
Target Class:
Epigenetic Regulator
Pathways:
Epigenetic Regulation
Research Area:
Aging • Cancer • Epigenetics • Metabolism
CAS No.:
304896-28-4
Molecular Weight:
434.27
Formula:
C₂₃H₁₃Cl₂N₃O₂
SMILES:
C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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