ACE2 Antibody - Western Blot Validated
BiCell Scientific
SKU:50410-WB-50UL
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Protein Function
Use this antibody to analyze ACE2 when mapping complex behavior and signaling context. ACE2 is a signaling protein that can relay information through phosphorylation and complex assembly. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring ACE2 alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
Workflow Perspective
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
When interpreting ACE2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the denaturing-format version to relate ACE2 behavior to upstream cues and downstream consequences.
- Targets:
- ACE2
- Research Area:
- Cardiovascular • Cell Signaling • Infectious Disease
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the N-terminal extracellular region of human ACE2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9BYF1
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C