Abietic Acid

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Selleck Chemicals

SKU:S5122-25MG

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Abietic Acid is an inhibitor of Lipoxygenase and PPAR gamma used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. It is especially relevant in endocrinology, inflammation, and metabolism models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.

By inhibiting Lipoxygenase and PPAR gamma, Abietic Acid can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In endocrinology, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Lipoxygenase and PPAR gamma
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Abietic Acid is appropriate when a defined chemical perturbant is needed to connect Lipoxygenase and PPAR gamma with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Lipoxygenase • PPAR gamma
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling • Metabolic Signaling
Research Area:
Endocrinology • Inflammation • Metabolism
CAS No.:
514-10-3
Molecular Weight:
302.45
Formula:
C₂₀H₃₀O₂
SMILES:
CC(C)C1=CC2=CCC3C(C2CC1)(CCCC3(C)C(=O)O)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.