A-740003

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Selleck Chemicals

S0826-5MG

€144,00 EUR
€144,00 EUR
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A-740003 is an antagonist of P2 Receptors and Interleukins used in studies of JAK-STAT Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in immunology, inflammation, and neuroscience models.

By blocking P2 Receptors and Interleukins, A-740003 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving P2 Receptors and Interleukins
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, A-740003 is appropriate when a defined chemical perturbant is needed to connect P2 Receptors and Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
P2 Receptors • Interleukins
Target Class:
GPCR
Pathways:
JAK-STAT Signaling • Immune Signaling • GPCR Signaling
Research Area:
Immunology • Inflammation • Neuroscience
CAS No.:
861393-28-4
Molecular Weight:
474.55
Formula:
C₂₆H₃₀N₆O₃
SMILES:
CC(C)(C)C(NC(=O)CC1=CC(=C(C=C1)OC)OC)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
InChIKey:
PUHSRMSFDASMAE-UHFFFAOYSA-N
PubChem:
72812793
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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