3,3'-Diindolylmethane

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Selleck Chemicals

SKU:S4728-100MG

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3,3'-Diindolylmethane is an antagonist of Androgen Receptor used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.

By blocking Androgen Receptor, 3,3'-Diindolylmethane can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Androgen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, 3,3'-Diindolylmethane is appropriate when a defined chemical perturbant is needed to connect Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Androgen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology
CAS No.:
1968-05-4
Molecular Weight:
246.31
Formula:
C₁₇H₁₄N₂
SMILES:
C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43
InChIKey:
VFTRKSBEFQDZKX-UHFFFAOYSA-N
PubChem:
3071
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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