{"product_id":"zo-3-tjp3-antibody-ffpe-validated","title":"ZO-3 (Tjp3) Antibody - FFPE Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eTo connect mechanism with measurement, this antibody lets you assess ZO-3 (Tjp3) in pathway-driven studies. ZO-3 is a structural regulator of intercellular boundaries and tissue architecture. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol Tjp3.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eMany targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for ZO-3 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing ZO-3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eUse the fixed-section version to relate ZO-3 (Tjp3) behavior to upstream cues and downstream consequences.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102283993433,"sku":"00239-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102284026201,"sku":"00239-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102284058969,"sku":"00239-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102284091737,"sku":"00239-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102284124505,"sku":"00239-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102284157273,"sku":"00239-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/zo3-liver-revised_3a7bb395-6457-48e7-832d-0ddd1960351c.jpg?v=1779283126","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/zo-3-tjp3-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}