{"product_id":"xevinapant-at406-s2754","title":"Xevinapant (AT406)","description":"\u003cp\u003e\u003cstrong\u003eXevinapant (AT406)\u003c\/strong\u003e is an antagonist of E3 Ligase used in studies of Apoptosis and Protein Degradation \/ Proteasome. It is especially relevant in apoptosis, cancer, and protein homeostasis models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking E3 Ligase, Xevinapant (AT406) can be used to examine caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving E3 Ligase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Protein Degradation \/ Proteasome\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Xevinapant (AT406) is appropriate when a defined chemical perturbant is needed to connect E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805711769945,"sku":"S2754-5MG","price":164.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805711802713,"sku":"S2754-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805711835481,"sku":"S2754-1G","price":4393.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805711868249,"sku":"S2754-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/AT-406-chemical-structure-s2754.gif?v=1776175638","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/xevinapant-at406-s2754","provider":"Absource Diagnostics","version":"1.0","type":"link"}