{"product_id":"wilforine-s0921","title":"Wilforine","description":"\u003cp\u003e\u003cstrong\u003eWilforine\u003c\/strong\u003e is an inhibitor of P-gp used in studies of transporter biology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to substrate uptake, efflux, and membrane-transport control in cancer and infectious disease models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting P-gp, Wilforine can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake\/efflux, and permeability assays, together with downstream-response mapping. In cancer and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving P-gp\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and infectious disease models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Wilforine is appropriate when a defined chemical perturbant is needed to connect P-gp with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805159235929,"sku":"S0921-5MG","price":195.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805159268697,"sku":"S0921-25MG","price":586.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0921-wilforine-chemical-structure.gif?v=1776172651","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/wilforine-s0921","provider":"Absource Diagnostics","version":"1.0","type":"link"}