{"product_id":"vvd-214-vvd-133214-ro7589831-e1966","title":"VVD-214 (VVD-133214, RO7589831)","description":"\u003cp\u003e\u003cstrong\u003eVVD-214 (VVD-133214, RO7589831)\u003c\/strong\u003e is an inhibitor linked to DNA Damage Response and Apoptosis and related pathway-oriented research. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects VVD-214 (VVD-133214, RO7589831) to DNA Damage Response and Apoptosis, supporting experiments that monitor checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions across biochemical, cellular, or phenotypic assay formats. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and dna damage \/ repair models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, VVD-214 (VVD-133214, RO7589831) is well suited to pathway-oriented studies that need a defined compound input for DNA Damage Response and Apoptosis readouts in apoptosis, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804550504793,"sku":"E1966-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804550537561,"sku":"E1966-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804550570329,"sku":"E1966-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804550603097,"sku":"E1966-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1966-VVD-214-chemical-structure.png?v=1776167520","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/vvd-214-vvd-133214-ro7589831-e1966","provider":"Absource Diagnostics","version":"1.0","type":"link"}