{"product_id":"urmc-099-s7343","title":"URMC-099","description":"\u003cp\u003e\u003cstrong\u003eURMC-099\u003c\/strong\u003e is an inhibitor of LRRK2 used in studies of MAPK \/ ERK Signaling and Autophagy. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting LRRK2, URMC-099 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and autophagic flux, lysosomal turnover, and stress adaptation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving LRRK2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Autophagy\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, URMC-099 is appropriate when a defined chemical perturbant is needed to connect LRRK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809475797337,"sku":"S7343-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809475830105,"sku":"S7343-25MG","price":468.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809475862873,"sku":"S7343-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/urmc-099-chemical-structure-s7343.gif?v=1776201265","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/urmc-099-s7343","provider":"Absource Diagnostics","version":"1.0","type":"link"}