{"product_id":"uqcrc1-antibody-sc-f1582","title":"Ubiquinol-Cytochrome C Reductase Core Protein I Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eUbiquinol-cytochrome c reductase core protein 1 (UQCRC1) is a core component of the mitochondrial ubiquinol-cytochrome c reductase complex (also known as the cytochrome bc1 complex or complex III), which is responsible for transferring electrons from coenzyme Q to cytochrome c, coupled with proton translocation across the inner mitochondrial membrane. This complex consists of 11 subunits, among which UQCRC1 is associated with cytochrome c to prevent apoptosis, and suppressing cytochrome c expression restores UQCRC1-mediated neurodegeneration. Depending on the literature source, UQCRC1 may also be discussed as Ubiquinol-Cytochrome C Reductase Core Protein I.\u003c\/p\u003e\u003cp\u003eReported cellular context includes mitochondrion inner membrane and cell membrane, which can matter when signal is compared across treatments or changing cell states. Following UQCRC1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eUQCRC1 is commonly interpreted in the context of apoptosis and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans mitochondrion inner membrane and cell membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between mitochondrion inner membrane and cell membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003eseparation of survival-associated changes from stress or death-associated readouts\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for UQCRC1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in UQCRC1 reflect biology rather than handling. When interpreting UQCRC1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep UQCRC1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577783460185,"sku":"F1582-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577783492953,"sku":"F1582-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577783525721,"sku":"F1582-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1582-IF.png?v=1773599904","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/uqcrc1-antibody-sc-f1582","provider":"Absource Diagnostics","version":"1.0","type":"link"}