{"product_id":"triciribine-api-2-s1117","title":"Triciribine (API-2)","description":"\u003cp\u003e\u003cstrong\u003eTriciribine (API-2)\u003c\/strong\u003e is an inhibitor of AKT and DNA\/RNA Synthesis and related targets used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs. It is especially relevant in cancer, cell signaling, and dna damage \/ repair models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting AKT and DNA\/RNA Synthesis and related targets, Triciribine (API-2) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving AKT and DNA\/RNA Synthesis and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Triciribine (API-2) is appropriate when a defined chemical perturbant is needed to connect AKT and DNA\/RNA Synthesis and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805224444249,"sku":"S1117-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57805224477017,"sku":"S1117-10MG","price":223.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805224509785,"sku":"S1117-50MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805224542553,"sku":"S1117-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805224575321,"sku":"S1117-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Triciribine-chemical-structure-S1117.gif?v=1776172939","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/triciribine-api-2-s1117","provider":"Absource Diagnostics","version":"1.0","type":"link"}