{"product_id":"tomm20-antibody-sc-f3252","title":"TOMM20 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eTOMM20 (Translocase of Outer Mitochondrial Membrane 20) is a receptor and key subunit of the TOM complex, essential for recognizing and translocating mitochondrial proteins from the cytosol into the mitochondria. It contains an N-terminal domain that binds mitochondrial targeting signals (MTS), which typically form amphipathic alpha helices, and works closely with TOM40 to facilitate protein import through the mitochondrial membrane. Depending on the literature source, TOMM20 may also be discussed as Tom20.\u003c\/p\u003e\u003cp\u003eReported cellular context includes membrane, mitochondrion, and mitochondrion outer membrane, which can matter when signal is compared across treatments or changing cell states. Following TOMM20 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eTOMM20 is commonly interpreted in the context of cancer, metabolism, and apoptosis research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans membrane, mitochondrion, and mitochondrion outer membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between membrane, mitochondrion, and mitochondrion outer membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003eseparation of survival-associated changes from stress or death-associated readouts\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for TOMM20. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in TOMM20 reflect biology rather than handling. When interpreting TOMM20, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep TOMM20 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578011558233,"sku":"F3252-20UL","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578011591001,"sku":"F3252-100UL","price":319.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578011623769,"sku":"F3252-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3252-IF.png?v=1773601061","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/tomm20-antibody-sc-f3252","provider":"Absource Diagnostics","version":"1.0","type":"link"}