{"product_id":"tlr7-8-agonist-1-dihydrochloride-e0639","title":"TLR7\/8 agonist 1 dihydrochloride","description":"\u003cp\u003e\u003cstrong\u003eTLR7\/8 agonist 1 dihydrochloride\u003c\/strong\u003e is an agonist of TLR used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.\u003c\/p\u003e\n\n\u003cp\u003eBy activating TLR, TLR7\/8 agonist 1 dihydrochloride can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TLR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, TLR7\/8 agonist 1 dihydrochloride is appropriate when a defined chemical perturbant is needed to connect TLR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804285018457,"sku":"E0639-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804285051225,"sku":"E0639-25MG","price":500.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0639-tlr7-8-agonist-1-dihydrochloride-chemical-structure.png?v=1776166193","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/tlr7-8-agonist-1-dihydrochloride-e0639","provider":"Absource Diagnostics","version":"1.0","type":"link"}