{"product_id":"tirasemtiv-ck-2017357-s0196","title":"Tirasemtiv (CK-2017357)","description":"\u003cp\u003e\u003cstrong\u003eTirasemtiv (CK-2017357)\u003c\/strong\u003e is annotated as an activator in this dataset and is relevant to biochemical and cell-based models. It is especially relevant in biochemical and cell-based models, where defined compound exposure can be linked to compound-linked biochemical, transcriptional, and phenotypic responses.\u003c\/p\u003e\n\n\u003cp\u003eBecause the current annotation identifies Tirasemtiv (CK-2017357) as an activator, it is suited to comparative profiling, concentration-response work, and follow-up studies that track compound-dependent signaling or phenotype changes without assuming a single assigned primary target. That positioning is consistent with gain-of-function pathway-activation studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. When a fully resolved mechanism is unavailable, parallel readouts such as viability, reporter activity, morphology, localization, or biochemical conversion can still help position the compound experimentally.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eGain-of-function pathway-activation studies\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003cli\u003eMechanism-oriented follow-up using biochemical and cellular endpoints\u003c\/li\u003e\n\u003cli\u003eBenchmarking of assay response across concentration ranges\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Tirasemtiv (CK-2017357) is appropriate for mechanism-oriented studies that require an activator-annotated compound for comparative profiling in biochemical and cell-based models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805087474009,"sku":"S0196-5MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805087506777,"sku":"S0196-25MG","price":390.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0196-tirasemtiv-chemical-structure.gif?v=1776171961","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/tirasemtiv-ck-2017357-s0196","provider":"Absource Diagnostics","version":"1.0","type":"link"}