{"product_id":"tenovin-3-s2176","title":"Tenovin-3","description":"\u003cp\u003e\u003cstrong\u003eTenovin-3\u003c\/strong\u003e is an inhibitor of Sirtuins and p53 used in studies of DNA Damage Response and Apoptosis and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions in aging, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Sirtuins and p53, Tenovin-3 can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In aging, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Sirtuins and p53\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Apoptosis and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Tenovin-3 is appropriate when a defined chemical perturbant is needed to connect Sirtuins and p53 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805449068889,"sku":"S2176-5MG","price":183.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805449101657,"sku":"S2176-25MG","price":665.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s2176-tenovin-3-chemical-structure.gif?v=1776174587","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/tenovin-3-s2176","provider":"Absource Diagnostics","version":"1.0","type":"link"}