{"product_id":"tacrine-e4822","title":"Tacrine","description":"\u003cp\u003e\u003cstrong\u003eTacrine\u003c\/strong\u003e is an inhibitor of AChR used in studies of DNA Damage Response and Neurotransmission. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and synaptic signaling, receptor activity, and neuronal excitability in cancer, dna damage \/ repair, and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting AChR, Tacrine can be used to examine checkpoint activation, DNA repair, and genome-stability control and synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays and electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, dna damage \/ repair, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving AChR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, dna damage \/ repair, and neuroscience models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Tacrine is appropriate when a defined chemical perturbant is needed to connect AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804965675353,"sku":"E4822-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804965708121,"sku":"E4822-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804965740889,"sku":"E4822-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804965773657,"sku":"E4822-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4822-Tacrine-chemical-structure.png?v=1776170140","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/tacrine-e4822","provider":"Absource Diagnostics","version":"1.0","type":"link"}