{"product_id":"sobetirome-e7120","title":"Sobetirome","description":"\u003cp\u003e\u003cstrong\u003eSobetirome\u003c\/strong\u003e is an agonist of Thyroid Hormone Receptor used in studies of Hormone Signaling. It is especially relevant in endocrinology models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy activating Thyroid Hormone Receptor, Sobetirome can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Thyroid Hormone Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Sobetirome is appropriate when a defined chemical perturbant is needed to connect Thyroid Hormone Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805038584153,"sku":"E7120-5MG","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E7120-Sobetirome-chemical-structure.png?v=1776171074","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/sobetirome-e7120","provider":"Absource Diagnostics","version":"1.0","type":"link"}