{"product_id":"smoothened-smo-or-frizzled-11-or-fzd11-antibody-ffpe-validated","title":"Smoothened (SMO or Frizzled-11 or FZD11) Antibody - FFPE Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eBuild reproducible readouts by using this antibody to characterize Smoothened across matched sample sets. Smoothened is a signaling protein that can relay information through phosphorylation and complex assembly. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.\u003c\/p\u003e\n\u003cp\u003eTracking Smoothened can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eParallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eIn sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. A brief pilot run can help set exposure ranges and reduce reruns later.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Smoothened, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eFor multi-run studies, the fixed-section option helps keep Smoothened trends comparable from experiment to experiment.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101640855897,"sku":"50611-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101640888665,"sku":"50611-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101640921433,"sku":"50611-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101640954201,"sku":"50611-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101640986969,"sku":"50611-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101641019737,"sku":"50611-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/smo-retina-pfa-0.5-5min_2bbfa718-e3cd-4c63-a7dc-f76c928a9349.jpg?v=1779280837","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/smoothened-smo-or-frizzled-11-or-fzd11-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}