{"product_id":"sklb-23bb-s8743","title":"SKLB-23bb","description":"\u003cp\u003e\u003cstrong\u003eSKLB-23bb\u003c\/strong\u003e is an inhibitor of HDAC used in studies of Cell Cycle Regulation and Epigenetic Regulation. It is especially relevant in cancer, cell cycle, and epigenetics models, where defined compound exposure can be linked to checkpoint control, mitotic progression, and proliferation timing and chromatin-state control, histone modification, and transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HDAC, SKLB-23bb can be used to examine checkpoint control, mitotic progression, and proliferation timing and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HDAC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Cell Cycle Regulation and Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, SKLB-23bb is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809642488153,"sku":"S8743-2MG","price":213.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809642520921,"sku":"S8743-25MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809642553689,"sku":"S8743-100MG","price":1936.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809642586457,"sku":"S8743-1G","price":3921.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/sklb-23bb-chemical-structure-s8743.gif?v=1776204692","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/sklb-23bb-s8743","provider":"Absource Diagnostics","version":"1.0","type":"link"}