{"product_id":"siponimod-baf312-s7179","title":"Siponimod (BAF312)","description":"\u003cp\u003e\u003cstrong\u003eSiponimod (BAF312)\u003c\/strong\u003e is an agonist of S1P Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating S1P Receptors, Siponimod (BAF312) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving S1P Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Siponimod (BAF312) is appropriate when a defined chemical perturbant is needed to connect S1P Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809461936473,"sku":"S7179-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809461969241,"sku":"S7179-25MG","price":390.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809462002009,"sku":"S7179-100MG","price":979.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809462034777,"sku":"S7179-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809462067545,"sku":"S7179-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/baf312-siponimod-chemical-structure-s7179.gif?v=1776201045","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/siponimod-baf312-s7179","provider":"Absource Diagnostics","version":"1.0","type":"link"}