{"product_id":"sew-2871-s7180","title":"SEW 2871","description":"\u003cp\u003e\u003cstrong\u003eSEW 2871\u003c\/strong\u003e is an agonist of S1P Receptors used in studies of PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling and related signaling programs. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.\u003c\/p\u003e\n\n\u003cp\u003eBy activating S1P Receptors, SEW 2871 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving S1P Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, SEW 2871 is appropriate when a defined chemical perturbant is needed to connect S1P Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809462100313,"sku":"S7180-2MG","price":490.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/S7180-SEW-2871-chemical-structure.png?v=1776201047","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/sew-2871-s7180","provider":"Absource Diagnostics","version":"1.0","type":"link"}