{"product_id":"setipiprant-act-129968-s5753","title":"Setipiprant (ACT-129968)","description":"\u003cp\u003e\u003cstrong\u003eSetipiprant (ACT-129968)\u003c\/strong\u003e is an antagonist of Prostaglandin Receptors used in studies of Immune Signaling and GPCR Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics in inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Prostaglandin Receptors, Setipiprant (ACT-129968) can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Prostaglandin Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Setipiprant (ACT-129968) is appropriate when a defined chemical perturbant is needed to connect Prostaglandin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57809280762201,"sku":"S5753-25MG","price":144.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/setipiprant-chemical-structure-s5753.gif?v=1776198795","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/setipiprant-act-129968-s5753","provider":"Absource Diagnostics","version":"1.0","type":"link"}