{"product_id":"s100-antibody-sc-f1617","title":"S100 β Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eS100 Β is a target of interest in many antibody-based workflows. S100 beta (also known as S100B) is a multifunctional, neuronal survival, calcium-binding protein predominantly found in astrocytes and various other cell types, including neurons, Schwann cells, and chondrocytes. It plays a dual role in the nervous system: promoting cell proliferation, migration, and survival while inhibiting apoptosis and differentiation. Depending on the literature source, S100 Β may also be discussed as S-100 (beta-Subunit) and S100B.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and nucleus, which can matter when signal is compared across treatments or changing cell states. Following S100 Β across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eS100 Β is commonly interpreted in the context of neuroscience and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for S100 Β. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in S100 Β reflect biology rather than handling. When interpreting S100 Β, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep S100 Β trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577795879257,"sku":"F1617-20UL","price":159.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577795912025,"sku":"F1617-100UL","price":349.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577795944793,"sku":"F1617-2X100UL","price":519.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1617-IF.png?v=1773599943","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/s100-antibody-sc-f1617","provider":"Absource Diagnostics","version":"1.0","type":"link"}