{"product_id":"rxra-antibody-sc-f1140","title":"Retinoid X Receptorα\/RXRA Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eRXRA is a member of the nuclear receptor (NR) superfamily, which primarily functions as transcriptional regulators involved in development, homeostasis, and metabolism. As a type II receptor, RXRA resides in the nucleus bound to DNA, repressing target gene expression without a ligand by interacting with corepressor complexes. Depending on the literature source, RXRA may also be discussed as Retinoid X Receptoralpha\/RXRA and Retinoid X Receptor alpha\/RXRA.\u003c\/p\u003e\u003cp\u003eReported cellular context includes nucleus, cytoplasm, and mitochondrion, which can matter when signal is compared across treatments or changing cell states. Following RXRA across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eRXRA is commonly interpreted in the context of metabolism, developmental biology, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans nucleus, cytoplasm, and mitochondrion, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between nucleus, cytoplasm, and mitochondrion across matched conditions\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for RXRA. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in RXRA reflect biology rather than handling. When interpreting RXRA, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep RXRA trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577624633689,"sku":"F1140-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577624666457,"sku":"F1140-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577624699225,"sku":"F1140-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1140-IF.png?v=1773599338","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/rxra-antibody-sc-f1140","provider":"Absource Diagnostics","version":"1.0","type":"link"}