{"product_id":"ro-90-7501-e7917","title":"Ro 90-7501","description":"\u003cp\u003e\u003cstrong\u003eRo 90-7501\u003c\/strong\u003e is an inhibitor of TLR used in studies of PI3K-Akt-mTOR Signaling and Immune Signaling and related signaling programs. It is especially relevant in cancer, dna damage \/ repair, and immunology models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-mediated signaling and inflammatory effector responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting TLR, Ro 90-7501 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cancer, dna damage \/ repair, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TLR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Immune Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Ro 90-7501 is appropriate when a defined chemical perturbant is needed to connect TLR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818684916057,"sku":"E7917","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e7917-ro-90-7501-chemical-structure-tube.png?v=1776276073","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ro-90-7501-e7917","provider":"Absource Diagnostics","version":"1.0","type":"link"}