{"product_id":"resatorvid-tak-242-s7455","title":"Resatorvid (TAK-242)","description":"\u003cp\u003e\u003cstrong\u003eResatorvid (TAK-242)\u003c\/strong\u003e is an inhibitor of TNF-alpha and Interleukins and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling in autophagy, immunology, and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting TNF-alpha and Interleukins and related targets, Resatorvid (TAK-242) can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In autophagy, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TNF-alpha and Interleukins and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Resatorvid (TAK-242) is appropriate when a defined chemical perturbant is needed to connect TNF-alpha and Interleukins and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809485955417,"sku":"S7455-5MG","price":154.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809485988185,"sku":"S7455-25MG","price":537.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809486020953,"sku":"S7455-100MG","price":1444.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809486053721,"sku":"S7455-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/tak-242-chemical-structure-s7455.gif?v=1776201418","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/resatorvid-tak-242-s7455","provider":"Absource Diagnostics","version":"1.0","type":"link"}