{"product_id":"rbfox3-antibody-sc-f0103","title":"NeuN Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eNEUN, also known as Fox-3, RBFOX3 (RNA binding protein, fox-1), or Fox-1 homolog C, is a 350 amino acid protein that contains one RRM (RNA recognition motif) domain. NEUN (Fox-3) is localized to both the nucleus and cytoplasm and contains an RNA recognition motif that functions as a splicing regulator and regulates alternative splicing events. Depending on the literature source, RBFOX3 may also be discussed as NeuN and RBFOX3\/NeuN.\u003c\/p\u003e\u003cp\u003eReported cellular context includes nucleus and cytoplasm, which can matter when signal is compared across treatments or changing cell states. Following RBFOX3 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eRBFOX3 is commonly interpreted in the context of neuroscience and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans nucleus and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between nucleus and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for RBFOX3. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in RBFOX3 reflect biology rather than handling. When interpreting RBFOX3, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep RBFOX3 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577383362905,"sku":"F0103-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577383395673,"sku":"F0103-100UL","price":379.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577383428441,"sku":"F0103-2X100UL","price":569.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0103-IF.png?v=1773598119","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/rbfox3-antibody-sc-f0103","provider":"Absource Diagnostics","version":"1.0","type":"link"}