{"product_id":"r-gne-140-s6675","title":"(R)-GNE-140","description":"\u003cp\u003e\u003cstrong\u003e(R)-GNE-140\u003c\/strong\u003e is an inhibitor of Dehydrogenases used in studies of Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to metabolic regulation, energy sensing, and enzyme-linked homeostasis in metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Dehydrogenases, (R)-GNE-140 can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Dehydrogenases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, (R)-GNE-140 is appropriate when a defined chemical perturbant is needed to connect Dehydrogenases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809407082841,"sku":"S6675-2MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809407115609,"sku":"S6675-5MG","price":223.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809407148377,"sku":"S6675-25MG","price":635.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809407181145,"sku":"S6675-100MG","price":1542.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809407213913,"sku":"S6675-1G","price":4904.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809407246681,"sku":"S6675-1ML\/DMSO","price":291.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/r-gne-140-chemical-structure-s6675.gif?v=1776200290","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/r-gne-140-s6675","provider":"Absource Diagnostics","version":"1.0","type":"link"}