{"product_id":"pyrroloquinoline-quinone-s3578","title":"Pyrroloquinoline quinone","description":"\u003cp\u003e\u003cstrong\u003ePyrroloquinoline quinone\u003c\/strong\u003e is an inhibitor of ROS used in studies of JAK-STAT Signaling and Oxidative Stress Response. It is especially relevant in aging, endocrinology, and immunology models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and redox signaling, ROS handling, and antioxidant defenses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ROS, Pyrroloquinoline quinone can be used to examine cytokine-responsive transcriptional signaling and immune regulation and redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In aging, endocrinology, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ROS\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Oxidative Stress Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Pyrroloquinoline quinone is appropriate when a defined chemical perturbant is needed to connect ROS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, endocrinology, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57808910909785,"sku":"S3578-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57808910942553,"sku":"S3578-25MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s3578-pyrroloquinoline-quinone-chemical-structure.gif?v=1776195072","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/pyrroloquinoline-quinone-s3578","provider":"Absource Diagnostics","version":"1.0","type":"link"}