{"product_id":"pt2385-s8352","title":"PT2385","description":"\u003cp\u003e\u003cstrong\u003ePT2385\u003c\/strong\u003e is an inhibitor of HIF used in studies of pathway modulation. It is especially relevant in cancer, cell signaling, and epigenetics models, where defined compound exposure can be linked to pathway-dependent signal amplification or attenuation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HIF, PT2385 can be used to examine pathway-dependent signal amplification or attenuation. This target class is commonly examined through pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping. In cancer, cell signaling, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HIF\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, cell signaling, and epigenetics models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, PT2385 is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57809603068249,"sku":"S8352-1MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809603101017,"sku":"S8352-5MG","price":291.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809603133785,"sku":"S8352-25MG","price":874.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809603166553,"sku":"S8352-100MG","price":1444.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/pt2385-chemical-structure-s8352.gif?v=1776202623","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/pt2385-s8352","provider":"Absource Diagnostics","version":"1.0","type":"link"}