{"product_id":"prickle2-epm5-antibody-western-blot-validated","title":"PRICKLE2 (EPM5) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody enables you to explore PRICKLE2 (EPM5) with a direct, biology-first readout. PRICKLE2 is a signaling protein that can relay information through phosphorylation and complex assembly. Focus on trends across conditions rather than single-point snapshots.\u003c\/p\u003e\n\u003cp\u003eFollowing PRICKLE2 across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eMany workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eThis denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing PRICKLE2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eSelect the denaturing-format version to keep PRICKLE2 (EPM5) interpretation aligned with your workflow goals.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101637218649,"sku":"50622-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101637251417,"sku":"50622-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101637284185,"sku":"50622-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101637316953,"sku":"50622-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101637349721,"sku":"50622-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101637382489,"sku":"50622-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/prickle2-e17-forebrain.jpg?v=1779280818","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/prickle2-epm5-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}