{"product_id":"prickle1-rilp-antibody-western-blot-validated","title":"PRICKLE1 (RILP) Antibody - Western Blot Validated","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around PRICKLE1 and use this antibody to analyze state-dependent differences. PRICKLE1 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eTracking PRICKLE1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Time course design can be decisive when regulation is transient or compartment dependent. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.\u003c\/p\u003e\n\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing PRICKLE1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing PRICKLE1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format option to keep PRICKLE1 analysis aligned with planned contrasts and endpoints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101637939545,"sku":"50621-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101637972313,"sku":"50621-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101638005081,"sku":"50621-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101638037849,"sku":"50621-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101638070617,"sku":"50621-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101638103385,"sku":"50621-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/prickle1-e17-forebrain.jpg?v=1779280822","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/prickle1-rilp-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}