{"product_id":"presenilin-1-psen1-or-ps1-or-ad3-antibody-western-blot-validated","title":"Presenilin-1 (PSEN1 or PS1 or AD3) Antibody - Western Blot Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to examine Presenilin-1 (PS1) when mapping complex behavior and signaling context. Presenilin-1 is a signaling protein that can relay information through phosphorylation and complex assembly. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol PS1.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eSince many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Presenilin-1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eThe denaturing-format option supports mechanistic reading of Presenilin-1 (PS1) when interactions and context are the focus.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101556085081,"sku":"51471-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101556117849,"sku":"51471-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101556150617,"sku":"51471-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101556183385,"sku":"51471-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101556216153,"sku":"51471-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101556248921,"sku":"51471-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/psen1brain.jpg?v=1779280371","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/presenilin-1-psen1-or-ps1-or-ad3-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}