{"product_id":"prc1-antibody-sc-f2440","title":"PRC1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eProtein Regulator of Cytokinesis 1 (PRC1) is a nonmotor microtubule-associated protein belonging to the MAP65\/ASE1 family, initially identified in budding yeast. Encoded by the PRC1 gene, this protein is essential for cytokinesis. PRC1 is regulated by CDK1, which keeps it in an inactive, monomeric form through phosphorylation.\u003c\/p\u003e\u003cp\u003eReported cellular context includes chromosome, cytoplasm, cytoskeleton, and microtubule, which can matter when signal is compared across treatments or changing cell states. Following PRC1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003ePRC1 is commonly interpreted in the context of cancer, stem cell biology, and cell cycle research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans chromosome, cytoplasm, and cytoskeleton, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between chromosome, cytoplasm, and cytoskeleton across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003estate transitions between self-renewal, priming, and differentiation\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in abundance, timing, or compartmental enrichment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for PRC1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in PRC1 reflect biology rather than handling. When interpreting PRC1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep PRC1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577945465177,"sku":"F2440-20UL","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577945497945,"sku":"F2440-100UL","price":289.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577945530713,"sku":"F2440-2X100UL","price":459.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2440-IF.png?v=1773600405","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/prc1-antibody-sc-f2440","provider":"Absource Diagnostics","version":"1.0","type":"link"}