{"product_id":"pioglitazone-u-72107-s2590","title":"Pioglitazone (U-72107)","description":"\u003cp\u003e\u003cstrong\u003ePioglitazone (U-72107)\u003c\/strong\u003e is an agonist of PPAR gamma and PPAR used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating PPAR gamma and PPAR, Pioglitazone (U-72107) can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PPAR gamma and PPAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Pioglitazone (U-72107) is appropriate when a defined chemical perturbant is needed to connect PPAR gamma and PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805676773721,"sku":"S2590-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805676806489,"sku":"S2590-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805676839257,"sku":"S2590-200MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805676872025,"sku":"S2590-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805676904793,"sku":"S2590-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Pioglitazone-Actos-chemical-structure-s2590.gif?v=1776175340","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/pioglitazone-u-72107-s2590","provider":"Absource Diagnostics","version":"1.0","type":"link"}