{"product_id":"pioglitazone-hcl-s2046","title":"Pioglitazone HCl","description":"\u003cp\u003e\u003cstrong\u003ePioglitazone HCl\u003c\/strong\u003e is an inhibitor of PPAR gamma used in studies of Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PPAR gamma, Pioglitazone HCl can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PPAR gamma\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Pioglitazone HCl is appropriate when a defined chemical perturbant is needed to connect PPAR gamma with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805398147417,"sku":"S2046-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805398180185,"sku":"S2046-50MG","price":291.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805398212953,"sku":"S2046-200MG","price":461.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805398245721,"sku":"S2046-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/pioglitazone-hydrochloride-actos-chemical-structure-s2046.gif?v=1776174403","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/pioglitazone-hcl-s2046","provider":"Absource Diagnostics","version":"1.0","type":"link"}