{"product_id":"pf-562271-besylate-s2672","title":"PF-562271 Besylate","description":"\u003cp\u003e\u003cstrong\u003ePF-562271 Besylate\u003c\/strong\u003e is an inhibitor of FAK and CDK1 and related targets used in studies of MAPK \/ ERK Signaling and Cell Cycle Regulation. It is especially relevant in angiogenesis, cancer, and cell cycle models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting FAK and CDK1 and related targets, PF-562271 Besylate can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving FAK and CDK1 and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Cell Cycle Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, PF-562271 Besylate is appropriate when a defined chemical perturbant is needed to connect FAK and CDK1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805690732889,"sku":"S2672-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805690765657,"sku":"S2672-50MG","price":802.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805690798425,"sku":"S2672-1G","price":3921.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/PF-00562271-chemical-structure-s2672.gif?v=1776175500","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/pf-562271-besylate-s2672","provider":"Absource Diagnostics","version":"1.0","type":"link"}