{"product_id":"park7-antibody-sc-f1047","title":"PARK7\/DJ1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003ePark7 (Parkinsonism-associated delicate), also known as DJ1, is an oncogene that regulates androgen receptor-dependent transcription, antioxidant responses, and intracellular signaling pathways by scavenging reactive oxygen species (ROS) and chaperoning selected proteins. It contains a reactive cysteine residue at position 106 (Cys106) responsible for its biological function. Depending on the literature source, PARK7 may also be discussed as PARK7\/DJ1 and DJ-1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cytoplasm, nucleus, and mitochondrion, which can matter when signal is compared across treatments or changing cell states. Following PARK7 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003ePARK7 is commonly interpreted in the context of neuroscience, oxidative stress, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasm, and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cytoplasm, and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eredox-associated shifts that may alter abundance, localization, or pathway coupling\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for PARK7. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in PARK7 reflect biology rather than handling. When interpreting PARK7, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep PARK7 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577596813657,"sku":"F1047-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577596846425,"sku":"F1047-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577596879193,"sku":"F1047-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1047-IF.png?v=1773599221","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/park7-antibody-sc-f1047","provider":"Absource Diagnostics","version":"1.0","type":"link"}