{"product_id":"otub2-in-1-e1880","title":"OTUB2-IN-1","description":"\u003cp\u003e\u003cstrong\u003eOTUB2-IN-1\u003c\/strong\u003e is an inhibitor of PD-1 \/ PD-L1 used in studies of Immune Signaling and Protein Degradation \/ Proteasome. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation in cancer, immunology, and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PD-1 \/ PD-L1, OTUB2-IN-1 can be used to examine cytokine-mediated signaling and inflammatory effector responses and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PD-1 \/ PD-L1\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and Protein Degradation \/ Proteasome\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, OTUB2-IN-1 is appropriate when a defined chemical perturbant is needed to connect PD-1 \/ PD-L1 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804528025945,"sku":"E1880-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804528058713,"sku":"E1880-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804528091481,"sku":"E1880-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804528124249,"sku":"E1880-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1880-OTUB2-IN-1-chemical-structure.png?v=1776167393","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/otub2-in-1-e1880","provider":"Absource Diagnostics","version":"1.0","type":"link"}