{"product_id":"ono-ae3-208-e2986","title":"ONO-AE3-208","description":"\u003cp\u003e\u003cstrong\u003eONO-AE3-208\u003c\/strong\u003e is an antagonist of Prostaglandin Receptors used in studies of Immune Signaling and GPCR Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics in inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Prostaglandin Receptors, ONO-AE3-208 can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Prostaglandin Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ONO-AE3-208 is appropriate when a defined chemical perturbant is needed to connect Prostaglandin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804654018905,"sku":"E2986-5MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804654051673,"sku":"E2986-25MG","price":372.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e2986-ONO-AE3-208-chemical-structure.png?v=1776168171","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ono-ae3-208-e2986","provider":"Absource Diagnostics","version":"1.0","type":"link"}